Hemoperfusion (Resin Adsorption) & Critical Diseases

Critical disease generally refers to serious disease (injury) with possible life-threatening occurences in a short time, such as infection-induced Sepsis and septic shock, non-infection-induced severe burns, severe trauma, severe acute pancreatitis and so on. These infections or non-infection factors will stimulate the body to produce an exaggerated inflammatory response, so that a large number of inflammatory mediators will be released including LPS as well as other pro-inflammatory cytokines and other anti-inflammation cytokines, which will be the central link in SIRS, Sepsis, CARS and MODS, and plays an important role in the diseases’ occurrence, development, prognosis and prognosis. As inflammatory mediators have features such as "waterfall cascades" and "network" and so on, early control of inflammatory response, blocking its development or effectively removing circulating inflammatory mediators may be the key to prevention and treatment of these syndrome, and it is very important for the treatment of critical disease.

HA330 resin hemoperfusion is a device designed specifically for critical disease patients, and the principle is to know the patients’ blood inflammatory mediators, to reduce or control the inflammatory response through the strong adsorption of HA resin, and then to effectively control the progress of SIRS.

Adsorption Principle

Adsorbent in HA330 resin hemoperfusion cartridge is the medical macroporous adsorptive resin processed by unique technology, whose adsorption capacity depends on the molecular sieve effect of three–dimensional network structure and the affinity between resin molecular groups

Product Properties

1.  Safe application: good biocompatibility, great mechanical strength of adsorbing material and stable adsorbability.

2.  High adsorption rate & large adsorption capacity

3.  Sterilization with γ ray , no bacterium or pyrogen

Application

1.  SIRS (Systemic Inflammatory Response Syndrome )

2.  Sepsis

3.  CARS (Compensatory Antiinflammatory Response Syndrome)

4.  MODS (Multiple Organ Dysfunction Syndrome)

5.  ANP (Acute Necrotizing Pancreatitis)

6.  Multiple Trauma, Crush Syndrome