---- Solution for Psoriasis, Rheumatism, Allergic Purpura ----
Cytokine plays an important role in dermatosis, autoimmune diseases & vasculitis.
Dermatosis:
The pathogenesis of psoriasis and pemphigus is complicated. A numer of documents evidenced that lymphoid factor generated by T-cell provokes epiderm proliferating, and enhances the inflammatory generateing that make the illness more serious, and the proliferation cutin makes the role enhanced of the activated T-cell by forming cell and releasing other cytokine, which forms vicious circle of mediated T-cell and it is the important pathogenesis of many skin diseases.
Autoimmune diseases:
Some cytokines will have a large quantity increase in inflammation, autoimmune disease, allergic diseases and shock, imbalance of proinflammatory factor and anti-inflammatory factor causes autoimmune disease such as SLE, rheumatoid arthritis, autoimmune hepatitis, multiple sarcitis, ulcerative colitis and endometriosis uterina, the level of inflammatory cytokine such as IL-1,IL-6,IL-2,TNF-α is improved obviously in the training supernatant of serum or joint synovial fluid or lymphocytes.
Vasculitis:
All sorts of vasculitis have complicated pathogenesis, involves inflammatory cells, cytokines, adhesion factors and so on. Due to some infection, endothelial exposure to certain antigens, triggering the outer membrane hemal wall and the dendritic cells of hemal wall in the film that has the ability of antigen to identify, devour and handle antigen, and express the collaborative stimulating factor and adhesion molecule by high level at the same time, activate the initial T cells, collecting mononuclear cells and macrophages to hemal wall, mediated vascular damaged, and the abnormal immune complex hemal wall in the pathogenesis of most vasculitis also play an important role.
Adsorption Principle
Adsorbent in HA280 resin hemoperfusion cartridge is the medical macroporous adsorptive resin. According to the properties of the immunity pathogenic factors, the pore sizes of resin particles, polarity of resin molecule groups, pore sizes of coating membrane, or lipophilic affinity of resin groups is adjusted to achieve specific adsorption.
Product Properties
1. Adsorption of relative specificity: relatively and specifically adsorb the cytokines and immunity mediators.
2. Safe application: good biocompatibility, great mechanical strength of adsorbing material and stable adsorbability.
3. Easy operation: whole blood adsorption which can be carried out on blood pump, hemoperfusion machine, hemodialysis machine & CRRT machine.
Clinical Verification
We have carried out hemoperfusion therapy in Changzheng Hospital Affiliated to the 2nd Military University of Medical Science, the 2nd Hospital Affiliated to Sichuan University , the 2nd Hospital Affiliated to Zhongnan University, the 3rd Hospital Affiliated to SUN YAT-SEN University, Jinan Central Hospital, Children’ Hospital of Jiangxi Province& Shengjing Hospital Affiliated to China Medical University, all achieving satisfied healing effect.
To evaluate the healing effect on Psoriasis and Allergic Purpura
|
disease
|
cases
|
excellent
|
effectual
|
null
|
effective rate
|
|
psoriasis
|
45
|
30
|
12
|
3
|
93%
|
|
allergic purpura
|
84
|
69
|
11
|
4
|
95.23%
|
The result shows that Jafron Hemoperfusion HA280 can effectively clear toxin which causes such disease.
Application
1. Dermatosis : psoriasis, pemphigus, chloasma, severe acne, severe drug rash
2. Autoimmune diseases: RA, SLE, Behcet disease, multiple sarcitis, AS, systemic scleroderma & sicca syndrome
3. Kinds of Vasculitis: allergic purpura, ANCA–associated vasculitis, urticarial vasculitis, polyarteritis nodosa, allergic vasculitis, Kawasaki disease
